43S起始前複合物

43S起始前複合物(英文：43S preinitiation complex,43S PIC)是一種核糖核蛋白複合物，存在於真核轉譯起始的早期階段。43S PIC包含由起始因子eIF1，eIF1A，eIF3和eIF2-Met-tRNA_i^Met-GTP三元復合物（eIF2-TC）結合的40S核糖體亞基。^[1][2][3][4]

功能

結構

參見

• 真核轉譯
• 40S核糖体亚基
• eIF3

參考資料

1. Sonenberg, Nahum; Hinnebusch, Alan G. Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets. Cell. 2009-02, 136 (4) [2022-08-28]. PMC 3610329 . PMID 19239892. doi:10.1016/j.cell.2009.01.042. （原始内容存档于2022-06-21） （英语）.
2. Aitken, Colin Echeverría; Lorsch, Jon R. A mechanistic overview of translation initiation in eukaryotes. Nature Structural & Molecular Biology. 2012-06, 19 (6) [2022-08-28]. ISSN 1545-9993. doi:10.1038/nsmb.2303. （原始内容存档于2022-08-28） （英语）.
3. Fraser, Christopher S. Quantitative studies of mRNA recruitment to the eukaryotic ribosome. Biochimie. Quality Control in Protein Synthesis. 2015-07-01, 114. ISSN 0300-9084. PMC 4458453 . PMID 25742741. doi:10.1016/j.biochi.2015.02.017 （英语）.
4. Hinnebusch, Alan G. Structural Insights into the Mechanism of Scanning and Start Codon Recognition in Eukaryotic Translation Initiation. Trends in Biochemical Sciences. 2017-08, 42 (8) [2022-08-28]. doi:10.1016/j.tibs.2017.03.004. （原始内容存档于2022-08-08） （英语）.