福爾哈德-埃德曼環化反應(Volhard-Erdmann cyclization),得名於德國化學家雅各布·福爾哈德及其學生胡戈·埃德曼[1],指通過丁二酸二鈉或其他1,4-雙官能團化合物(如γ-酮酸、1,4-二酮、氯乙醯取代的酯)與七硫化四磷作用發生環化,合成烴基芳基噻吩化合物。

例如,從衣康酸合成3-甲基噻吩:[2]

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參見

參考資料

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