Rice High School。后来毕业于芝加哥的帝博大學。 1992年,他与独立电影制片人艾莉森·迪基(Alison Dickey)结婚,並且育有二子。 萊利本身為素食主義者。 Interview: John C. Reilly (页面存档备份,存于互联网档案馆). Retrieved 2009-05-19
to talk about his life experiences and rough times growing up in Jersey City. Luke attended Snyder, but graduated from Linden High." Derek Luke在互联网电影资料库(IMDb)上的資料(英文)