17α-羥孕烯醇酮(英語:17α-Hydroxypregnenolone)是一種孕烷類(C21)甾體物質,由孕烯醇酮在C17的α位羥基化而來。體內的17α-羥孕烯醇酮由腎上腺生殖腺粒線體細胞色素P450氧化酶——17α-羥化酶(CYP17A1)氧化而來。人類體內的17α-羥孕烯醇酮在青春期末達到高峰,隨後下降[1],在孕期也有較高濃度。

Quick Facts 藥物動力學數據, 藥物代謝 ...
17α-羥孕烯醇酮
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藥物動力學數據
藥物代謝Adrenal, Gonads
識別資訊
  • 3β,17α-dihydroxypregn-5-en-20-one
CAS號387-79-1  checkY
PubChem CID
ChemSpider
ChEBI
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.006.239 編輯維基數據鏈接
化學資訊
化學式C21H32O3
摩爾質量332.48 g/mol
3D模型(JSmol英語JSmol
熔點268 °C(514 °F)
  • CC[C@@]2(O)CC[C@H]1[C@@H]3CCC4CC(O)C(=O)C[C@]4(C)[C@H]3CC[C@@]12C
  • InChI=1S/C21H34O3/c1-4-21(24)10-8-16-14-6-5-13-11-17(22)18(23)12-19(13,2)15(14)7-9-20(16,21)3/h13-17,22,24H,4-12H2,1-3H3/t13?,14-,15+,16+,17?,19+,20+,21-/m1/s1 checkY
  • Key:QPLFSAZMHUAMKE-FOCOMJRBSA-N checkY
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類固醇激素生成途徑與酶

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參考文獻

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