螯合效應指出,生成螯合物的反應比生成普通非螯合配合物的反應在能量上更有利。它主要由兩個因素導致,一是熵增作用——螯合反應熵變高過普通配位反應,因需用配體分子數較少;另一則是焓作用——同一多齒配體減少了多個配位點原子間的相互排斥,有利於促進螯合物的生成。

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