大安東尼婭(拉丁語:Antonia maior,前39年出生)是馬克·安東尼和小屋大薇的長女,儒略-克勞狄王朝的成員。
第一代羅馬皇帝奧古斯都是她的舅父,她的妹妹小安東尼婭娶了奧古斯都的繼子德盧蘇斯前23年左右,大安東尼婭本人和盧基烏斯·多米提烏斯·阿赫諾巴爾比結婚,兩人共有1子2女:
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