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壯穴科（學名：Fellodistomidae）是吸蟲綱斜睪目之下的一個科[1]。
本科之下包含以下亞科：
- Asymmetrinae
- Fellodistominae Nicoll, 1909
- Piriforminae Skrjabin & Koval, 1957
- 頸褶亞科 Tergestiinae Skrjabin & Koval, 1957
包括下列屬：[2]
- Allosteringophorus Machida, 1987
- Asymmetra Bilqees, Khalil, Khan, Perveen et Haseeb, 2016
- Benthotrema Manter, 1934
- Cercaria Müller, 1773
- Choanomyzus Manter et Crowcroft, 1950
- Complexobursa Oshmarin et Mamaev, 1963
- Coomera Dove et Cribb, 1995
- Elopsium Fischthal et Thomas, 1972
- Fellodistomum Stafford, 1904
- Gymnotergestia Nahhas et Cable, 1964
- Hypertrema Manter, 1960
- Lintonium Stunkard et Nigrelli, 1930
- Lissoloma Manter, 1934
- Lomasoma Manter, 1935
- Megalomyzon Manter, 1947
- Megenteron Manter, 1934
- Mesolecitha Linton, 1910
- Monascus Looss, 1907
- Neomegalomyzon Machida, Kamegai et Kuramochi, 2007
- Oceroma Cribb, Miller, Bray et Cutmore, 2014
- Olssonium Bray et Gibson, 1980
- Piriforma Yamaguti, 1938
- Proctoeces Odhner, 1911
- Prudhoeus Bray et Gibson, 1980
- Pseudobenthotrema Machida, Kamegai et Kuramochi, 2007
- Pseudohypertrema Bilqees, 1976
- Pseudosteringophorus Yamaguti, 1940
- Pycnadenoides Tamaguti, 1938
- Steringophorus Odhner, 1905
- Steringotrema Odhner, 1911
- Steringovermes Bray, 2004
- Symmetrovesicula Yamaguti, 1938
- 頸褶屬 Tergestia Stossich, 1899
- Theledera Linton, 1910
- Thryssatrema Sailaja et Madhavi, 2012
- Varelacreptotrema Gomes & de Fábio, 1971
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