藍色螢光蛋白（英語：Blue Fluorescent Protein，縮寫BFP）是一種綠色螢光蛋白（GFP）的變體，能發出藍色螢光（激發峰約380nm，發射峰約440nm），其與GFP的區別在於蛋白質序列66號位的酪氨酸變為組氨酸，145號位的酪氨酸變為苯丙氨酸[1]，其晶體結構已解析[2]。
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