Kelly、Etter、Jorgensen、Hine、Curran、Göbel和De Mendoza(參見下文引用的參考文獻)在非金屬小分子氫鍵催化領域作出了開創性貢獻。Peter R. Schreiner及其同事確定並引入了缺電子的硫脲衍生物作為氫鍵有機催化劑。Schreiner的選擇的硫脲為N,N'-二[3,5-二(三氟甲基)苯基]硫脲,這種催化劑結合了雙氫鍵介導的有機催化劑的所有結構特徵:
Christian M. Kleiner, Peter R. Schreiner. Hydrophobic amplification of noncovalent organocatalysis. Chem. Commun. 2006: 4315–4017.
Z. Zhang and P. R. Schreiner. Thiourea-Catalyzed Transfer Hydrogenation of Aldimines. Synlett. 2007, 2007 (9): 1455–1457. doi:10.1055/s-2007-980349.
Wanka, Lukas; Chiara Cabrele; Maksims Vanejews; Peter R. Schreiner. γ-Aminoadamantanecarboxylic Acids Through Direct C–H Bond Amidations. European Journal of Organic Chemistry. 2007, 2007 (9): 1474–1490. ISSN 1434-193X. doi:10.1002/ejoc.200600975.
Kotke, Mike; Schreiner, Peter R. (Thio)urea Organocatalysts. Petri M. Pihko (編). Hydrogen Bonding in Organic Synthesis. October 2009: 141 to 251 [2022-01-15]. ISBN 978-3-527-31895-7. (原始內容存檔於2014-01-15).
Alexander Wittkopp, Peter R. Schreiner, "Diels-Alder Reactions in Water and in Hydrogen-Bonding Environments", book chapter in "The Chemistry of Dienes and Polyenes" Zvi Rappoport (Ed.), Volume 2, John Wiley & Sons Inc.; Chichester, 2000, 1029-1088. ISBN0-471-72054-2.
Alexander Wittkopp, "Organocatalysis of Diels-Alder Reactions by Neutral Hydrogen Bond Donors in Organic and Aqueous Solvents", dissertation written in German, Universität Göttingen, 2001. English abstract/download:
Peter R. Schreiner, review: "Metal-free organocatalysis through explicit hydrogen bonding interactions", Chem. Soc. Rev.2003, 32, 289-296. abstract/download:
Yoshiji Takemoto, review: "Recognition and activation by ureas and thioureas: stereoselective reactions using ureas and thioureas as hydrogen-bonding donors", Org. Biomol. Chem.2005, 3, 4299-4306. abstract/download: Mark S. Taylor, Eric N. Jacobsen. Asymmetric Catalysis by Chiral Hydrogen-Bond Donors. Angewandte Chemie International Edition. 2006, 45 (10): 1520–1543. PMID 16491487. doi:10.1002/anie.200503132.J. C. Stephen. Organocatalysis Mediated by (Thio)urea Derivatives. Chemistry: A European Journal. 2006, 12 (21): 5418–5427. PMID 16514689. doi:10.1002/chem.200501076.
Kotke, Mike; Peter Schreiner. Generally Applicable Organocatalytic Tetrahydropyranylation of Hydroxy Functionalities with Very Low Catalyst Loading. Synthesis. 2007, 2007 (5): 779–790. ISSN 0039-7881. doi:10.1055/s-2007-965917.
Wittkopp, Alexander; Peter R. Schreiner. Metal-Free, Noncovalent Catalysis of Diels–Alder Reactions by Neutral Hydrogen Bond Donors in Organic Solvents and in Water. Chemistry: A European Journal. 2003, 9 (2): 407–414. ISSN 0947-6539. PMID 12532289. doi:10.1002/chem.200390042.
A. Wittkopp and P. R. Schreiner. Metal-Free, Noncovalent Catalysis of Diels-Alder Reactions by Neutral Hydrogen Bond Donors in Organic Solvents and in Water. Chemistry: A European Journal. 2003, 9 (2): 407–414. PMID 12532289. doi:10.1002/chem.200390042.
Sigman, Matthew S.; Eric N. Jacobsen. Schiff Base Catalysts for the Asymmetric Strecker Reaction Identified and Optimized from Parallel Synthetic Libraries. Journal of the American Chemical Society. 1998, 120 (19): 4901–4902. ISSN 0002-7863. doi:10.1021/ja980139y.
Okino, Tomotaka; Yasutaka Hoashi; Yoshiji Takemoto. Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts. Journal of the American Chemical Society. 2003, 125 (42): 12672–12673. ISSN 0002-7863. PMID 14558791. doi:10.1021/ja036972z.
McCooey, Séamus H.; Stephen J. Connon. Urea- and Thiourea-Substituted Cinchona Alkaloid Derivatives as Highly Efficient Bifunctional Organocatalysts for the Asymmetric Addition of Malonate to Nitroalkenes: Inversion of Configuration at C9 Dramatically Improves Catalyst Performance. Angewandte Chemie International Edition. 2005, 44 (39): 6367–6370. ISSN 1433-7851. PMID 16136619. doi:10.1002/anie.200501721.
Wanka, Lukas; Chiara Cabrele; Maksims Vanejews; Peter R. Schreiner. γ-Aminoadamantanecarboxylic Acids Through Direct C–H Bond Amidations. European Journal of Organic Chemistry. 2007, 2007 (9): 1474–1490. ISSN 1434-193X. doi:10.1002/ejoc.200600975.
Li, Xiao-Juan; Kun Liu; Hai Ma; Jing Nie; Jun-An Ma. Highly Enantioselective Michael Addition of Malonates to Nitroolefins Catalyzed by Chiral Bifunctional Tertiary Amine-Thioureas Based on Saccharides. Synlett. 2008, 2008 (20): 3242–3246. ISSN 0936-5214. doi:10.1055/s-0028-1087370.
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