甘露聚糖結合凝集素

甘露聚糖結合凝集素（英語：Mannose-binding lectin，縮寫MBL，也被稱為甘露糖結合蛋白或甘露聚糖結合蛋白，英語：mannan-binding protein，縮寫MBP）是一種在先天免疫系統中起作用的凝集素^[1][2]。

Mannose-binding lectin (protein C) 2, soluble 甘露糖結合凝集素（蛋白C）2，可溶
PDB rendering based on 1hup.
有效結構 PDB 直系同源檢索：PDBe, RCSB PDB查詢代碼列表 1HUP
標識
代號	MBL2; COLEC1; HSMBPC; MBL; MBL2D; MBP; MBP-C; MBP1; MBPD
擴展標識	遺傳學：154545 鼠基因：96924 同源基因：110436 ChEMBL: 1795113 GeneCards: MBL2 Gene
基因本體論描述 分子功能 · receptor binding · protein binding · mannose binding · eukaryotic cell surface binding · calcium-dependent protein binding · bacterial cell surface binding 細胞成分 · extracellular region · collagen · extracellular space 生物過程 · complement activation, lectin pathway · acute-phase response · complement activation · complement activation, classical pathway · response to oxidative stress · opsonization · negative regulation of growth of symbiont in host · innate immune response · positive regulation of phagocytosis · defense response to Gram-positive bacterium · killing by host of symbiont cells Sources: Amigo / QuickGO
RNA表達模式
更多表達數據
直系同源體
物種	人類	小鼠
Entrez	4153	17195
Ensembl	ENSG00000165471	ENSMUSG00000024863
UniProt	P11226	P41317
mRNA序列	NM_000242	NM_010776
蛋白序列	NP_000233	NP_034906
基因位置	Chr 10: 54.53 – 54.53 Mb	Chr 19: 30.23 – 30.24 Mb
PubMed查詢	[1]	[2]
閱 論 編

外部連接

• 醫學主題詞表（MeSH）：Mannan-Binding+Lectin

參考文獻

1. Fraser IP, Koziel H, Ezekowitz RA. The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity.. Semin. Immunol. 1998, 10 (5): 363–72. PMID 9799711. doi:10.1006/smim.1998.0141.
2. Worthley DL, Bardy PG, Mullighan CG. Mannose-binding lectin: biology and clinical implications.. Internal medicine journal. 2005, 35 (9): 548–55. PMID 16105157. doi:10.1111/j.1445-5994.2005.00908.x.