First-in-man study

Kling D, Jamois C, Schick E, Solier C, Benghozi R, Gaudreault J. First-in-Man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin. J

（原始内容存档于2020-01-23）.  Alltucker, Ken. First case of coronavirus in US: Patient got pneumonia, but now only has cough, study says. USA Today. January 31, 2020

物安全性数据而推导出的拟用于人体可能产生临床药理学作用剂量的1/100，同时，最大剂量不超过100ug的剂量。 Ⅰ期临床试验（英语：First-in-man study）也称临床药理和毒理作用试验期。其是对已通过临床前安全性和有效性评价的新药在人体上验证其安全性。即是根据预先设计的计量，从初始安全剂

University of Illinois Press, 1965: ASIN B000BANHI6. The first serious bio-bibliographical study. van der Poel, Marc. Cornelius Agrippa, the Humanist Theologian

was the first to use electron microscope to study biological cells. Earlier electron microscopes were used only in physical researches. His first electron