Arp2/3复合物（英语：Arp2/3 complex）是一个包含7个次单元的蛋白质，专门调控肌动蛋白（actin）细胞骨架。其中Arp2与Arp3属于肌动蛋白相关蛋白（Actin-Related Proteins），能对微丝进行核化（nucleation）。整个复合物则能够与微丝结合，并且使促使新的微丝生成。
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