1-氨甲基-5-甲氧基茚满

1-氨甲基-5-甲氧基茚满（英语：1-Aminomethyl-5-methoxyindane，简称AMMI），是一种由普渡大学的大卫·厄尔·尼科尔斯领导的团队开发的药物，它作为选择性血清素释放剂并与和DiFMDA具有相似亲和力的血清素转运蛋白结合。^[1][2]

1-氨甲基-5-甲氧基茚满

临床资料
给药途径	口服
ATC码	未分配
法律规范状态
法律规范	失控
识别信息
IUPAC命名法 (5-Methoxy-2,3-dihydro-1H-inden-1-yl)methanamine
CAS号	1415750-28-5  Y[EPA]
PubChem CID	45091234
ChemSpider	24205063 Y
UNII	585V6BDH9X
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID801029881
化学信息
化学式	C11H15NO
摩尔质量	177.25 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像
SMILES NCC1CCc2c1ccc(OC)c2
InChI InChI=1S/C11H15NO/c1-13-10-4-5-11-8(6-10)2-3-9(11)7-12/h4-6,9H,2-3,7,12H2,1H3 Y Key:WPBKCMLYKMDWRD-UHFFFAOYSA-N Y

参见

• 2CB-Ind

参考资料

1. Roman DL, Saldaña SN, Nichols DE, Carroll FI, Barker EL. Distinct molecular recognition of psychostimulants by human and Drosophila serotonin transporters. The Journal of Pharmacology and Experimental Therapeutics. February 2004, 308 (2): 679–87. PMID 14593087. S2CID 6439942. doi:10.1124/jpet.103.057836.
2. Walline CC, Nichols DE, Carroll FI, Barker EL. Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition. The Journal of Pharmacology and Experimental Therapeutics. June 2008, 325 (3): 791–800. PMC 2637348 . PMID 18354055. doi:10.1124/jpet.108.136200.