1,3,3,5,5-五甲基环己胺

1,3,3,5,5-五甲基环己胺
临床资料
ATC码	未分配;
识别信息
	IUPAC命名法 1,3,3,5,5-pentamethylcyclohexanamine; ;
CAS号	219810-59-0
PubChem CID	6433106;
ChemSpider	4938294 ;
UNII	856DX0KJ84;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID40176399 ;
ECHA InfoCard	100.107.752
化学信息
化学式	C11H23N
摩尔质量	169.31 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CC1(CC(CC(C1)(C)N)(C)C)C;
	InChI InChI=1S/C11H23N/c1-9(2)6-10(3,4)8-11(5,12)7-9/h6-8,12H2,1-5H3 ; Key:OGZQTTHDGQBLBT-UHFFFAOYSA-N ;

1,3,3,5,5-五甲基环己胺（英语：1,3,3,5,5-pentamethylcyclohexanamine，或称为Neramexane）是一种美金刚胺相关药物，分子式为C₁₁H₂₃N^[1]，作为一种NMDA受体拮抗剂^[2]，具有神经保护作用^[3]。

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参考文献

[1]
Gilling K, Jatzke C, Wollenburg C, Vanejevs M, Kauss V, Jirgensons A, Parsons CG. A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization. Journal of Neural Transmission. 2007, 114 (12): 1529–37. PMID 17728997. S2CID 8654883. doi:10.1007/s00702-007-0792-7.
[2]
Danysz W, Parsons CG, Jirgensons A, Kauss V, Tillner J. Amino-alkyl-cyclohexanes as a novel class of uncompetitive NMDA receptor antagonists. Current Pharmaceutical Design. 2002, 8 (10): 835–43. PMID 11945134. doi:10.2174/1381612024607117.
[3]
Danysz W, Parsons CG. Neuroprotective potential of ionotropic glutamate receptor antagonists. Neurotoxicity Research. March 2002, 4 (2): 119–26. PMID 12829411. S2CID 9413469. doi:10.1080/10298420290015872.