阿穆鲁尼-马尼亚大区（马达加斯加语：Amoron'i Mania）是马达加斯加的23个大区之一，位于该国中部，北临瓦基南卡拉特拉大区，东毗阿齐纳纳纳大区和瓦图瓦维大区，南接上马齐亚特拉大区，西邻梅纳贝大区，首府是安布西特拉，下分4县，面积16,141平方公里，2004年人口约693,200。
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