足蛋白（podocin、nephrosis 2, idiopathic, steroid-resistant）即肾脏的组成肾元之肾小体内的鲍氏囊上之足细胞裂隙隔膜(slit diaphragm)的蛋白质成分。肾小球毛细血管内皮细胞，肾小球基底膜及裂隙隔膜充当的肾小球滤过屏障。[1]足蛋白基因NPHS2的突变能引起肾病症候群(NS)，如局灶节段性肾小球硬化症(FSGS)或微小病变(MCD)。[2]
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