前229年(秦王政十八年、赵幽缪王七年),领兵抵抗秦军的赵国大将李牧被赵王宠臣郭开进谗言害死,副将司马尚被撤换。赵幽缪王派赵葱和齐国将领颜聚代替他们率军抵抗秦国。前228年(秦王政十九年、赵幽缪王八年),秦将王翦率军击败赵军,赵葱被秦兵杀死,颜聚逃到邯郸,和赵幽缪王一起被秦军俘虏。
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