葡萄糖-6-磷酸脱氢酶

葡萄糖-6-磷酸脱氢酶
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	1QKI、2BH9、2BHL
识别号
别名	G6PD；, G6PD1, glucose-6-phosphate dehydrogenase, Glucose-6-phosphate dehydrogenase
外部ID	OMIM：305900 MGI：105977 HomoloGene：37906 GeneCards：G6PD
相关疾病
	贫血
基因位置（人类）
染色体	X染色体
终止	154,547,572 bp
基因位置（小鼠）
染色体	小鼠5号染色体
终止	61,968,506 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• protein homodimerization activity; • glucose binding; • 血浆蛋白结合; • NADP binding; • 相同蛋白质结合; • oxidoreductase activity; • carbohydrate binding; • glucose-6-phosphate dehydrogenase activity; • oxidoreductase activity, acting on CH-OH group of donors;
细胞组分	• 细胞质; • 细胞质基质; • 膜; • cytoplasmic side of plasma membrane; • 外排体; • 细胞核; • 细胞内膜结合细胞器; • 微管组织中心;
生物学过程	• NADP metabolic process; • response to organic cyclic compound; • substantia nigra development; • glutathione metabolic process; • NADPH regeneration; • pentose-phosphate shunt, oxidative branch; • 脂质代谢; • regulation of neuron apoptotic process; • ribose phosphate biosynthetic process; • pentose biosynthetic process; • negative regulation of protein glutathionylation; • 磷酸戊糖途径; • glucose metabolic process; • response to food; • cellular response to oxidative stress; • cholesterol biosynthetic process; • glucose 6-phosphate metabolic process; • response to ethanol; • erythrocyte maturation; • positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; • negative regulation of reactive oxygen species metabolic process; • negative regulation of cell growth involved in cardiac muscle cell development; • response to iron(III) ion; • 碳水化合物代谢;
	Sources:Amigo / QuickGO
直系同源
	2539
	14380
	ENSG00000160211
	ENSMUSG00000089992
	P11413
	P97324
	NM_000402; NM_001042351; NM_001360016
	NM_019468
	NP_000393; NP_001035810; NP_001346945
	NP_062341
	维基数据
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