单固(?—251年),字恭夏,山阳郡(治今山东省金乡县西北)人,三国曹魏官员。

单固为人有器度。正始年间,单固被兖州刺史令狐愚辟为别驾。开始不愿应命,其母夏侯氏劝他,遂以母命而去,担任州别驾。后令狐愚与其舅父太尉王凌通谋反对司马懿,单固参与他们的计划。密谋败露,因单固知而不言,司马懿于是收捕单固和家属系于廷尉,后斩杀。

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