维基百科中的医学内容
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脏器逆位(situs inversus,situs transversus)亦称内脏反位[1](situs oppositus),是一种先天性的结构缺陷,症状是患者的内脏各器官的位置与一般人正好左右相反(镜像颠倒),譬如患者的心脏位在右手边,肝脏位在左手边。这种先天缺陷现象较罕见,大约万人里才有一个(1/10000)[2]。
Quick Facts 脏器逆位 situs inversus, 分类和外部资源 ...
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脏器逆位一般与常染色体隐性基因有关,此外,患有先天性心脏病患病的比率相对偏高,患者的健康状况一般与普通人无甚明显区别,许多患者是一直到自己的X光片才知道自己的内脏位置与其他人不一样,且呈现镜像对称现象。[3]
卡塔格内综合征(Kartagener syndrome)是原发性纤毛运动不良症的一种类型,并有脏器逆位。
存档副本. [2023-12-22]. (原始内容存档于2023-12-22).
- McManus, Chris. Right Hand, Left Hand. Harvard University Press. 2002. ISBN 0-674-00953-3. this book was the 2003 Aventis winner and has a description of the history behind the discovery of thisTemplate:Vague medical condition.
- Yokoyama T, Copeland NG, Jenkins NA, Montgomery CA, Elder FF, Overbeek PA. Reversal of left-right asymmetry: a situs inversus mutation. Science. 1993, 260 (5108): 679–682. PMID 8480178. doi:10.1126/science.8480178.
- Lowe LA, Supp DM, Sampath K, et al. Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature. 1996, 381 (6578): 158–161. PMID 8610013. doi:10.1038/381158a0.
- Levin M. Left-right asymmetry in vertebrate embryogenesis. BioEssays. 1997, 19 (4): 287–296. PMID 9136626. doi:10.1002/bies.950190406.
- Levin M, Pagan S, Roberts DJ, Cooke J, Kuehn MR, Tabin CJ. Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo. Dev. Biol. 1997, 189 (1): 57–67. PMID 9281337. doi:10.1006/dbio.1997.8662.
- Logan M, Pagán-Westphal SM, Smith DM, Paganessi L, Tabin CJ. The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. Cell. 1998, 94 (3): 307–317. PMID 9708733. doi:10.1016/S0092-8674(00)81474-9.
- Stern CD, Wolpert L. Left-right asymmetry: all hands to the pump. Curr. Biol. 2002, 12 (23): R802–803. PMID 12477404. doi:10.1016/S0960-9822(02)01312-X.