丁烷雌酚

丁烷雌酚（英语：Butestrol）是一种有机化合物，化学式C₁₆H₁₈O₂^[1]，属于人工合成的非甾体雌激素^[2]，从未上市^[3]，结构上与乙烯雌酚及其衍生物类似^[4]。

丁烷雌酚

left: (S,S)-butestrol right: (R,R)-butestrol
临床资料
其他名称	Butoestrol; Racemic butestrol; rac-Butestrol; dl-Butestrol; Isobutestrol
药物类别（英语：Drug class）	Nonsteroidal estrogen
识别信息
IUPAC命名法 4-[(2R,3R)-3-(4-hydroxyphenyl)butan-2-yl]phenol
CAS号	5776-76-1  Y
PubChem CID	197049
ChemSpider	170656
UNII	9S69QHQ4DU
化学信息
化学式	C16H18O2
摩尔质量	242.32 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像
SMILES C[C@@H](C1=CC=C(C=C1)O)[C@@H](C)C2=CC=C(C=C2)O
InChI InChI=1S/C16H18O2/c1-11(13-3-7-15(17)8-4-13)12(2)14-5-9-16(18)10-6-14/h3-12,17-18H,1-2H3/t11-,12-/m1/s1 Key:GDUYFVYTXYOMSJ-VXGBXAGGSA-N

参考文献

1. Terenius L. Effect of synthetic oestrogens and analogues on the uptake of oestradiol by the immature mouse uterus and vagina. Acta Pharmacologica et Toxicologica. 1966, 24 (1): 89–100. PMID 6012750. doi:10.1111/j.1600-0773.1966.tb00371.x.
2. Martin L, Cox RI, Emmens CW. Further studies on the effects of oestrogens and anti-oestrogens on early pregnancy in mice. Reproduction. 1963, 5 (2): 239–247. ISSN 1470-1626. S2CID 84972967. doi:10.1530/jrf.0.0050239.
3. Martin L, Claringbold PJ. The mitogenic action of oestrogens in the vaginal epithelium of the ovariectomized mouse. The Journal of Endocrinology. May 1960, 20 (3): 173–186. PMID 14421704. doi:10.1677/joe.0.0200173.
4. Emmens CW, Cox RI, Martin L. The oestrogenic and anti-oestrogenic activity of compounds related to diethylstilboestrol. Acta Endocrinologica. 1964, 45 (4_Suppl): SUPPL90:61–SUPPL90:69. PMID 14117596. doi:10.1530/acta.0.045s061.