小核RNA(英语:small nuclear RNA,常见缩写snRNA,也见译为核内小RNA),是含有100到300碱基RNA

它参与真核生物细胞核RNA的加工。snRNA和许多蛋白质结合在一起成为小胞核核糖核蛋白snRNPssmall nuclear ribonucleoproteins),参与信使RNA前体(pre-mRNA)的剪接,使后者成为成熟mRNA

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