2-吡啶甲酸苄酯

2-吡啶甲酸苄酯是一种有机化合物，化学式为C₁₃H₁₁NO₂。它可由2-吡啶甲酰氯和苯甲醇在三乙胺存在下反应制得。^[3]它和4-氯溴苄反应，可以得到4-氯苄基吡啶𬭩-2-甲酸苄酯溴化物。^[2]

2-吡啶甲酸苄酯
别名	吡啶-2-甲酸苯甲酯
识别
CAS号	71653-37-7  Y
SMILES	O=C(OCC=1C=CC=CC1)C2=NC=CC=C2
性质
化学式	C13H11NO2
摩尔质量	213.23 g·mol−1
外观	无色油状物[1][2]
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

参考文献

1. Raghunath Reddy Anugu, Sailu Munnuri, and John R. Falck. Picolinate-Directed Arene meta-C–H Amination via FeCl3 Catalysis. J. Am. Chem. Soc. 2020, 142, 11, 5266–5271. doi:10.1021/jacs.9b13753.
2. Zhi Yang, Hanlin Chen, Linxi Wan, Xinyi Feng, Lingshuang Ma, Pei Tang, Fen-Er Chen. Sustainable synthesis of long-acting local anesthetics ropivacaine and levobupivacaine under batch and continuous flow via asymmetric hydrogenation. Org. Chem. Front. 2024. 11. 2891-2896. doi:10.1039/D4QO00072B.
3. Ju Yuel Baek, Yong-Joo Shin, Heung Bae Jeon, Kwan Soo Kim. Picolinyl group as an efficient alcohol protecting group: cleavage with Zn(OAc)2·2H2O under a neutral condition. Tetrahedron Letters. 2005. 46 (31): 5143-5147. doi:10.1016/j.tetlet.2005.05.125.