东晋时担任监军。咸和五年(330年)十月,成汉大将军李寿、征南将军费黑攻打东晋的巴东郡、建平郡,将其攻克,担任巴东郡太守的杨谦和监军毌丘奥退守宜都。后来他担任假节、监巴东诸军事、益州刺史。永和年间,振威将军周抚接替他担任假节、监巴东诸军事、益州刺史。
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