度戈妥珠单抗(INN:Duligotuzumab)是一种双特异性人源化IgG1单克隆抗体,设计用于治疗癌症。它充当免疫调节剂并与EGFR和HER3结合。[1][2]它由罗氏公司开发。针对头颈癌和结直肠癌的临床开发已停止,但与考比替尼联合使用的I期试验正在评估实体瘤治疗的安全性。[3]
单克隆抗体 | |
---|---|
种类 | 完整抗体 |
目标 | HER3 |
临床资料 | |
ATC码 |
|
识别信息 | |
CAS号 | 1314238-96-4 |
ChemSpider |
|
UNII | |
KEGG |
参考资料
Wikiwand in your browser!
Seamless Wikipedia browsing. On steroids.
Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.
Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.