头孢噻利INN:Cefoselis)是第四代头孢菌素。在日本和中国临床广泛用于治疗各种革兰氏阳性革兰氏阴性感染。2014年的一项研究表明,头孢噻利可有效治疗呼吸道尿路感染[1]

Quick Facts 头孢噻利, 识别 ...
头孢噻利
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IUPAC名
(6R,7R)-3-[[3-amino-2-(2-hydroxyethyl)pyrazol-1-ium-1-yl]methyl]-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
别名 Wincef
识别
CAS号 122841-10-5  checkY
PubChem 5748845
ChemSpider 16736411
SMILES
 
  • CO/N=C(\C1=CSC(=N1)N)/C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=C(N4CCO)N)C(=O)[O-]
InChI
 
  • 1/C19H22N8O6S2/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28/h2-3,8,13,17,20,28H,4-7H2,1H3,(H4,21,22,23,29,31,32)/b24-12-/t13-,17-/m1/s1
InChIKey BHXLLRXDAYEMPP-SBGRAJFYBO
性质
化学式 C19H22N8O6S2
摩尔质量 522.56 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。
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