麥克法迪恩-史蒂文斯反應(McFadyen-Stevens reaction)指鹼催化下,酰基磺酰肼發生熱分解,生成相應的醛類。[1][2]
![Thumb](http://upload.wikimedia.org/wikipedia/commons/thumb/3/3a/McFadyen-Stevens_Reaction_Scheme.png/640px-McFadyen-Stevens_Reaction_Scheme.png)
達德曼等發展了一種不同的酰肼試劑。[3]
反應機理
反應的具體機理仍不很清楚。有認為[4][5]反應機理是由底物的去質子化、質子1,2-遷移以及斷裂反應所組成,最後一步中烷氧負離子斷裂,得到產物,並生成芳基亞磺酸根離子(5)、放出氮氣。
![Thumb](http://upload.wikimedia.org/wikipedia/commons/thumb/3/36/McFadyen-Stevens_Reaction_Mechanism.png/640px-McFadyen-Stevens_Reaction_Mechanism.png)
參見
參考資料
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