DEP結構域(英語:DEP domain)是一種球狀的蛋白質結構域,名字來源於散亂蛋白、Egl-10和普列克底物蛋白(Dishevelled, Egl-10 and Pleckstrin)的首字母縮寫,含有約80個氨基酸殘基,與G蛋白信號通路有關[1]。
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