Glial cell line-derived neurotrophic factor

Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer Therapy. The AAPS Journal. November 2020

factor receptor）是细胞表面结合生长因子的受体，是生长因子信号在细胞中级联放大的第一步。 作为配體的生长因子与受体结合通常会给与细胞生长或分化的信号。 生长因子受体通常通过JAK/STAT、MAP激酶和PI3激酶等途径起作用。 醫學主題詞表（MeSH）：Growth+Factor+Receptors

Kobayashi K, Hagiwara K. Epidermal growth factor receptor (EGFR) mutation and personalized therapy in advanced nonsmall cell lung cancer (NSCLC). Targeted Oncology

Gazit A, Gilon C, Levitzki A. Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins. J Biol Chem. 1993, 268 (15): 11134–42

figitumumab, targeting the insulin-like growth factor-1 receptor, for the treatment of patients with non-small-cell lung cancer. Clinical Lung Cancer. July 2009