组氨酸脱羧酶

基因本體論描述
分子功能	· carboxy-lyase activity · lyase activity · amino acid binding · histidine decarboxylase activity · pyridoxal phosphate binding
細胞成分	· dendrite · insoluble fraction · cytosol · soluble fraction · cell soma
生物過程	· carboxylic acid metabolic process · catecholamine biosynthetic process · histamine metabolic process · histidine metabolic process · histidine catabolic process · cellular amino acid and derivative metabolic process
Sources: Amigo / QuickGO

直系同源體

物種

人類

小鼠

mRNA序列

蛋白序列

基因位置

Chr 15:
48.32 – 48.35 Mb

Chr 2:
126.42 – 126.44 Mb

PubMed查詢

[1]

[2]

關閉

C₆H₉N₃O₂ → C₅H₉N₃ + CO₂

在人體中，組氨酸脫羧酶由HDC基因編碼。^[4]^[5]

生物胺組織胺在許多生理過程中有重要的調節作用，包括神經傳遞、胃酸分泌、平滑肌舒張。從組氨酸到組織胺的生物合成由L-組氨酸脫羧酶催化。這個同源二聚體酶是一個依賴磷酸吡哆醛（PLP）的脫羧酶，並對其底物組氨酸有高度特異性。^[4]

參考

擴展閱讀

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外部連結

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