生發中心(英語:Germinal center,又譯生長中心)是淋巴器官包括淋巴結脾臟B細胞繁殖、分化以及抗體基因變異的區域[1]。在機體發揮正常免疫功能對抗感染時,抗體在生發中心會改變它們的類別,例如從IgM變成IgG

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