生平
宣德五年(1430年)登進士,授兵部主事。正統年間,再升至職方司郎中。郕王監國時,于謙薦擢為兵部右侍郎。京師保衛戰時,于謙在城外禦敵,吳寧則在城中掌管兵部事。景泰元年,以病乞退,之後不再復出,在家居三十餘年後去世。吳寧有識鑒之才,曾經為于謙選擇女婿,認定千戶朱驥。于謙感到疑惑,吳寧則稱:「公他日當得其力。」後于謙被殺,朱驥果然出面歸葬于謙。[1]
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