鄭妃（?—?），南北朝後期人物。
鄭氏原為北齊武成帝高湛長子高綽的王妃，武平五年（574年），韓鳳誣告高綽謀反，齊後主高緯讓胡人何猥薩扼殺高綽。北周滅亡北齊後，鄭氏被周武帝所寵幸。她請求將高綽下葬。周武帝下詔葬高綽於永平陵北。鄭妃與荊王宇文元的母親鄭姬為一人或兩人，已不可考。
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