鄰苯二甲酸單苄酯

鄰苯二甲酸單苄酯（英語：Monobenzyl phthalate，縮寫MBzP，IUPAC名為2-苯甲氧基羰基苯甲酸，2-phenylmethoxycarbonylbenzoic acid）是一種結構簡式為C₆H₅CH₂OOCC₆H₄COOH的有機化合物。MBzP為鄰苯二甲酸丁苄酯在人體內的主要初級代謝產物，多於另一種水解產物鄰苯二甲酸單丁酯 (MBP)^[2][3]。和其它許多鄰苯二甲酸酯一樣，MBzP也是一種內分泌干擾物^[4][5]。

鄰苯二甲酸單苄酯
IUPAC名 2-phenylmethoxycarbonylbenzoic acid[1]
別名	Phthalic Acid Monobenzyl Ester[1] Benzyl hydrogen phthalate[1] 1,2-Benzenedicarboxylic acid, mono(phenylmethyl) ester[1] Mono(phenylmethyl) 1,2-benzenedicarboxylate[1] 2-phenylmethoxycarbonylbenzoic acid[1]
識別
CAS號	2528-16-7
PubChem	31736
ChemSpider	29430
SMILES	C1=CC=C(C=C1)COC(=O)C2=CC=CC=C2C(=O)O
ChEBI	132612
性質
化學式	C15H12O4
摩爾質量	256.25 g·mol−1
危險性
GHS危險性符號
GHS提示詞	Warning
H-術語	H319
P-術語	P264, P280, P305+351+338, P337+313
若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

參考文獻

1. Monobenzyl phthalate. PubChem. National Center for Biotechnology Information, U.S. National Library of Medicine. February 29, 2020 [March 5, 2020]. （原始內容存檔於2020-08-03）.
2. Huang, Jingyu; Nkrumah, Philip N.; Li, Yi; Appiah-Sefah, Gloria. Chemical Behavior of Phthalates Under Abiotic Conditions in Landfills. Reviews of Environmental Contamination and Toxicology 224. New York, NY: Springer Science+Business Media. 2013: 39–52. ISBN 9781461458814. PMID 23232918. doi:10.1007/978-1-4614-5882-1_2.
3. Saillenfait AM, Sabaté JP, Gallissot F. Comparative embryotoxicities of butyl benzyl phthalate, mono-n-butyl phthalate and mono-benzyl phthalate in mice and rats: in vivo and in vitro observations. Reproductive Toxicology. 2002, 17 (5): 575–83. PMID 14555196. doi:10.1016/s0890-6238(03)00102-3.
4. Ema M, Harazono A, Miyawaki E, Ogawa Y. Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the plasticizer n-butyl benzyl phthalate, in rats. Toxicology Letters. July 1996, 86 (1): 19–25. PMID 8685916. doi:10.1016/0378-4274(96)03665-x.
5. Ema M, Harazono A, Miyawaki E, Ogawa Y. Characterization of developmental toxicity of mono-n-benzyl phthalate in rats. Reproductive Toxicology. 1995, 10 (5): 365–72. PMID 8888408. doi:10.1016/0890-6238(96)00082-2.