胸腺嘧啶二聚體(英語:Thymine dimer)是指相鄰的DNA分子中的兩個胸腺嘧啶共價鍵相連,一般是由紫外線的照射,或是其他化學突變原所造成。是DNA損害的例子之一。DNA修復系統中負責刪除修復可將這些損害辨認出來,並將其修補。對許多生物而言,光裂合酶能直接將二聚體分離,進而完成修復。

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