特他洛爾

特他洛爾
臨床資料
AHFS/Drugs.com	國際藥品名稱
給藥途徑	口服
ATC碼	C07AA16 (WHO) ;
法律規範狀態
法律規範	處方藥（℞-only）;
識別資訊
	IUPAC命名法 (±)-1-(tert-Butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol; ;
CAS號	83688-84-0
PubChem CID	36920;
IUPHAR/BPS	571;
ChemSpider	33875 ;
UNII	9ZO341YQXP;
KEGG	D07182 ;
ChEMBL	ChEMBL434200 ;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID80865735 ;
ECHA InfoCard	100.073.179
化學資訊
化學式	C16H25NO2S
摩爾質量	295.44 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
手性	外消旋體
	SMILES CC(C)(C)NCC(COC1=CC=CC2=C1SCCC2)O;
	InChI InChI=1S/C16H25NO2S/c1-16(2,3)17-10-13(18)11-19-14-8-4-6-12-7-5-9-20-15(12)14/h4,6,8,13,17-18H,5,7,9-11H2,1-3H3 ; Key:HTWFXPCUFWKXOP-UHFFFAOYSA-N ;

特他洛爾（英語：Tertatolol），商品名Artex、Artexal、Prenalex，是一種β受體阻滯劑，用於治療高血壓。它是由法國施維雅製藥公司發現的，並在歐洲銷售。^[1]

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特他洛爾還被證明可作為血清素5-HT_1A和5-HT_1B受體拮抗劑，類似於普萘洛爾和吲哚洛爾。^[2]^[3]^[4]

參見

[1]
Swiss Pharmaceutical Society. Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. 2000. ISBN 3-88763-075-0.
[2]
Langlois M, Brémont B, Rousselle D, Gaudy F. Structural analysis by the comparative molecular field analysis method of the affinity of beta-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptors. European Journal of Pharmacology. January 1993, 244 (1): 77–87. PMID 8093601. doi:10.1016/0922-4106(93)90061-d.
[3]
Jolas T, Haj-Dahmane S, Lanfumey L, Fattaccini CM, Kidd EJ, Adrien J, et al. (-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. May 1993, 347 (5): 453–463. PMID 7686633. S2CID 22129922. doi:10.1007/bf00166735.
[4]
van Wijngaarden I, Soudijn W, Tulp MT. 5-HT_1A Receptors. Soudijn W, Olivier B, van Wijngaarden I (編). Serotonin Receptors and Their Ligands. Amsterdam: Elsevier. 1997. ISBN 0-444-82041-8.