奎尼酸脫氫酶(英語:quinate dehydrogenase,EC 1.1.1.24 (頁面存檔備份,存於互聯網檔案館))是一種以NAD+或NADP+為受體、作用於供體CH-OH基團上的氧化還原酶。這種酶能催化以下酶促反應:
奎尼酸脫氫酶 | |||||||||
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識別碼 | |||||||||
EC編號 | 1.1.1.24 | ||||||||
CAS號 | 9028-28-8 | ||||||||
數據庫 | |||||||||
IntEnz | IntEnz瀏覽 | ||||||||
BRENDA | BRENDA入口 | ||||||||
ExPASy | NiceZyme瀏覽 | ||||||||
KEGG | KEGG入口 | ||||||||
MetaCyc | 代謝路徑 | ||||||||
PRIAM | 概述 | ||||||||
PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
基因本體 | AmiGO / EGO | ||||||||
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上述反應中的NAD+不能以NADP+替代。奎尼酸脫氫酶以奎尼酸為特異性底物,而苯丙酮酸、苯丙氨酸、肉桂酸和莽草酸則不能作為底物。這種酶主要參與苯丙氨酸、酪氨酸和色氨酸的生物合成過程。
參考文獻
- Gamborg OL. Aromatic metabolism in plants. III. Quinate dehydrogenase from mung bean cell suspension cultures. Biochim. Biophys. Acta. 1966, 128: 483–491.
- MITSUHASHI S, DAVIS BD. Aromatic biosynthesis. XIII. Conversion of quinic acid to 5-dehydroquinic acid by quinic dehydrogenase. Biochim. Biophys. Acta. 1954, 15 (2): 268–80. PMID 13208693. doi:10.1016/0006-3002(54)90069-4.
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