國家人類基因組研究所(英語:National Human Genome Research Institute,縮寫NHGRI)是美國國家衛生院(National Institutes of Health,NIH)的下屬研究所,位於馬里蘭州貝塞斯達。NHGRI最初為NIH的負責籌辦國際人類基因組計劃(Human Genome Project,HGP)的辦公室,1989年成立[1]。
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