普圖馬約河（西班牙語：Río Putumayo，葡萄牙語：Rio Içá）是南美洲亞馬遜河的一條支流，成為哥倫比亞與厄瓜多爾或秘魯接壤的界線。
現時普圖馬約河是主要的航道，基本全部河道可通航。
普圖馬約河兩岸居民主要從事養牛業和橡膠貿易。
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