鲁宾逊-加布里尔合成是2-酰胺基-脱水,生成𫫇唑化学反应

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鲁宾逊-加布里尔合成

历史上,脱水剂是浓硫酸。后来发现,用三氯氧磷也可以成功。

2-酰胺基-酮可以用达金-维斯特反应来合成。

参考文献

  • Robinson, R. J. Chem. Soc. 1909, 95, 2167.
  • Gabriel, S. Ber. 1910, 43, 134.
  • Gabriel, S. Ber. 1910, 43, 1283.

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