肺癌部的惡性肿瘤,起源于組織细胞不受控制地生長(英语:cell growth )。如治疗不及时,肿瘤细胞将很可能转移至鄰近組織或其他身體部位。肺部最常見的原發性惡性腫瘤屬於上皮癌,可粗分為小细胞癌(SCLC)和非小细胞癌(英语:non-small-cell lung
厄洛替尼Kobayashi K, Hagiwara K. Epidermal growth factor receptor (EGFR) mutation and personalized therapy in advanced nonsmall cell lung cancer (NSCLC). Targeted
第二信使系统 第二信使(英语:Second messenger)在生物学里是胞内信号分子,负责细胞内的信号转导以触发生理变化,如增殖(英语:Cell growth )、细胞分化、迁移、存活和细胞凋亡。因此第二信使是细胞内的信号转导的启动组成部件之一。第二信使分子的例子包括:环腺苷酸(cAMP)、環磷酸鳥苷(cGM
阿法替尼Cancer. Cell ,100(1), pp.57-70. Wieduwilt MJ, Moasser MM. The epidermal growth factor receptor family: biology driving targeted therapeutics. Cell Mol Life
血小板衍生生長因子endothelial cell growth , and placenta growth factor (PlGF) which is also active in angiogenesis. PDGF plays a role in embryonic development, cell proliferation