4-甲氧基苯丙炔酸

4-甲氧基苯丙炔酸是一种有机化合物，化学式为C₁₀H₈O₃。它可由4-乙炔基苯甲醚和二氧化碳在碳酸铯存在下、氟硼酸银催化下于二甲基亚砜中反应，反应结束后调节pH得到。^[2]它和氯化亚砜反应，可以得到4-甲氧基苯丙炔酰氯。^[3]在氧化银、乙酸钯催化下，它和三苯基铋发生脱羧偶合反应，可以得到4-甲氧基二苯乙炔。^[4]

4-甲氧基苯丙炔酸
英文名	4-Methoxyphenylpropynoic acid
识别
CAS号	2227-57-8  Y
性质
化学式	C10H8O3
摩尔质量	176.17 g·mol−1
熔点	141-143 °C（分解）[1]
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

参考文献

1. Bergmann, Ernst; Bondi, Alfred. Modes of action of phosphorus pentachloride. III. Action on acetylene derivatives. Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen, 1933. 66B: 278-286. ISSN 0365-9488.
2. Matthias Arndt, Eugen Risto, Thilo Krause, Lukas J. Gooßen. CH Carboxylation of Terminal Alkynes Catalyzed by Low Loadings of Silver(I)/DMSO at Ambient CO2 Pressure. ChemCatChem. 2012-04, 4 (4): 484–487 [2021-11-20]. doi:10.1002/cctc.201200047 （英语）.
3. Max Deimling, Manuel Kirchhof, Barbara Schwager, Yaseen Qawasmi, Alex Savin, Tina Mühlhäuser, Wolfgang Frey, Birgit Claasen, Angelika Baro, Thomas Sottmann, Sabine Laschat. Asymmetric Catalysis in Liquid Confinement: Probing the Performance of Novel Chiral Rhodium–Diene Complexes in Microemulsions and Conventional Solvents. Chemistry – A European Journal. 2019-07-17, 25 (40): 9464–9476 [2021-11-20]. ISSN 0947-6539. doi:10.1002/chem.201900947 （英语）.
4. Kishor Eknath Balsane, Sitaram Haribhau Gund, Jayashree Milind Nagarkar. Base free palladium-Ag2O catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with triarylbismuth reagents. Catalysis Communications. 2018-01, 104: 78–81 [2021-11-20]. doi:10.1016/j.catcom.2017.10.018. （原始内容存档于2018-06-17） （英语）.