1-异硫氰基-6-甲亚磺酰基己烷

1-异硫氰基-6-甲亚磺酰基己烷
	IUPAC名; 1-Isothiocyanato-6-(methanesulfinyl)hexane
别名	6-MITC; 6-MSITC; 异硫氰酸(6-甲亚磺酰基)己酯; (6-甲基亚磺酰基)己基硫氰酸酯
识别
CAS号	4430-35-7
PubChem	9815648
ChemSpider	7991398
SMILES	CS(=O)CCCCCN=C=S;
ChEBI	138799
性质
化学式	C8H15NOS2
摩尔质量	205.34 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

1-异硫氰基-6-甲亚磺酰基己烷或异硫氰酸-6-甲亚磺酰基己酯是一种有机化合物，化学式为C₈H₁₅NOS₂。它可由6-溴己腈、甲硫醇钠、二硫化碳和间氯过氧苯甲酸为原料反应得到。^[1]它存在于山葵中，是一种糖原合酶激酶3β（英语：GSK-3）抑制剂。^[2]有文献对其抗癌作用做了小鼠实验。^[3]

Quick Facts 1-异硫氰基-6-甲亚磺酰基己烷, 识别 ...

Close

参考文献

[1] [1]
Ashida, Hitoshi; Hashimoto, Takashi. Cell cycle inhibitors containing Brassicaceae isothiocyanates, and topical preparations, cosmetics, and health foods containing them. 2006 JP 2006089394 A.

[2] [2]
Jun Yoshida, Satomi Nomura, Naoyuki Nishizawa, Yoshiaki Ito, Ken-ichi Kimura. Glycogen Synthase Kinase-3β Inhibition of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi ( Wasabia japonica Matsum). Bioscience, Biotechnology, and Biochemistry. 2011-01-23, 75 (1): 136–139 [2022-02-26]. ISSN 0916-8451. doi:10.1271/bbb.100507 （英语）.

[3] [3]
Yoko Fuke, Yoshiko Haga, Haruhiro Ono, Takahiro Nomura, Kazuo Ryoyama. Anti-carcinogenic activity of 6-methylsulfinylhexyl isothiocyanate-, an active anti-proliferative principal of wasabi (Eutrema wasabi Maxim.). Cytotechnology. 1997-11-01, 25 (1): 197 [2022-02-26]. ISSN 1573-0778. PMC 3466737 . PMID 22358892. doi:10.1023/A:1007918508115 （英语）.

[1]

[2]

[3]