陈致虚(1290年~?)为元代著名道教金丹派学者、内丹家。字观吾,号上阳子庐陵(今江西吉安)人。著名的内丹理论家,他将金丹派推向全真道,成为全真南宗。

天历二年(1329年),遇赵友钦(号缘督子)于湖南衡阳,受其所传金丹之道。其后,又遇青城老人,传以“先天一气坎月离日金丹之旨”。著有《金丹大要》十六卷。

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