艾地苯醌(英语:Idebenone)是一种有机化合物,化学名:6-(10-羟基癸基)-2,3-二甲氧基-5-甲基-1,4-苯醌,分子式C19H30O5,是辅酶Q10结构类似物,由武田药品工业开发作为治疗阿兹海默症认知疾病的药物使用[1]

Quick Facts 临床资料, 商品名(英语:Drug nomenclature) ...
艾地苯醌
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临床资料
商品名英语Drug nomenclatureCatena, Raxone, Sovrima
AHFS/Drugs.com国际药品名称
核准状况
ATC码
法律规范状态
法律规范
  • 处方药(-only)
药物动力学数据
生物利用度<1% (high first pass effect)
血浆蛋白结合率>99%
生物半衰期18 hours
排泄途径Urine (80%) and feces
识别信息
  • 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-
    cyclohexa-2,5-diene-1,4-dione
CAS号58186-27-9  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C19H30O5
摩尔质量338.44 g·mol−1
3D模型(JSmol英语JSmol
  • O=C1/C(=C(\C(=O)C(\OC)=C1\OC)C)CCCCCCCCCCO
  • InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 checkY
  • Key:JGPMMRGNQUBGND-UHFFFAOYSA-N checkY
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