至高条款（Supremacy Clause）是在美国宪法第六条第二款的条款。此条款明确表示了宪法、联邦法律及美国对外条约为“全国之最高法律”（"the supreme law of the land"）。此条款确立它们为美国法律体系的最高层次法律，强制各州法官捍卫它们，即使它们抵触州宪法及州法律。
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全文
This Constitution, and the Laws of the United States which shall be made in Pursuance thereof; and all Treaties made, or which shall be made, under the Authority of the United States, shall be the supreme Law of the Land; and the Judges in every State shall be bound thereby, any thing in the Constitution or Laws of any State to the Contrary notwithstanding.[1]
本宪法及依本宪法所制定之合众国法律；以及合众国已经缔结及将要缔结的一切条约，皆为全国之最高法律；每个州的法官都应受其约束，任何一州宪法或法律中的任何内容与之抵触时，均不得有违这一规定。
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