圣弗朗索瓦县(英语:Saint Francois County)是美国密苏里州东南部的一个县。面积1,172平方公里。根据美国2000年人口普查,共有人口55,641人。县治法明顿(Farmington)。
![Thumb](http://upload.wikimedia.org/wikipedia/commons/thumb/6/6a/Map_of_Missouri_highlighting_Saint_Francois_County.svg/640px-Map_of_Missouri_highlighting_Saint_Francois_County.svg.png)
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