Remove ads

双氢睾酮(英语:Dihydrotestosterone,简称为DHT,又称5α-二氢睾酮)[1]是一种雄性激素。双氢睾酮在前列腺睾丸毛囊以及肾上腺中被5α还原酶合成出来。此酶催化还原睾酮这种激素分子结构中4号位与5号位之间的双键。而5α-还原酶抑制剂可以抑制男性进一步脱发。[2]

事实速览 临床资料, 怀孕分级 ...
双氢睾酮
临床资料
怀孕分级
  • X
给药途径肌内注射、透皮给药
ATC码
药物动力学数据
生物利用度Oral 0-2%
药物代谢Hepatic
排泄途径Renal
识别信息
  • (5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17
    -tetradecahydrocyclopenta[a]phenanthren-3-one [来源请求]
    OR
    (1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-5-one
CAS号521-18-6  checkY
PubChem CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.007.554 编辑维基数据链接
化学信息
化学式C19H30O2
摩尔质量290.442 g/mol
3D模型(JSmol英语JSmol
  • O=C4C[C@@H]3CC[C@@H]2[C@H](CC[C@]1(C)[C@@H](O)CC[C@H]12)[C@@]3(C)CC4
  • InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1 checkY
  • Key:NVKAWKQGWWIWPM-ABEVXSGRSA-N checkY
关闭
事实速览 “双氢睾酮”的各地常用名称, 中国大陆 ...
“双氢睾酮”的各地常用名称
中国大陆双氢睾酮[1]
台湾二氢睾酮
关闭

参考文献

参见

Wikiwand in your browser!

Seamless Wikipedia browsing. On steroids.

Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.

Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.

Remove ads