DU145(DU-145)是人类前列腺癌细胞系。DU145、PC3和LNCaP被认为是用于治疗研究的标准前列腺癌细胞系[1]。DU145细胞系源自原发性前列腺腺癌的中枢神经系统远端转移,在顶枕开颅手术 (parietooccipital craniotomy) 中被切除[2]雄激素受体阳性的DU145对激素不敏感,并且不表达前列腺特异抗原。 DU145细胞与具有高转移潜力的PC3细胞相比,具有中等的转移潜力[3]

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依托泊苷诱导的DU145细胞凋亡。

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