60S核糖体亚基

60S亚基（英语：Eukaryotic large ribosomal subunit (60S)）是真核80S核糖体的大亚基，“60S”是核糖体颗粒根据其沉降系数以斯维德伯格单位来表示及命名的，它在结构和功能上与70S原核核糖体的50S亚基有关。^{[1][2][3][4][5][6]}但是，60S亚基比原核50S亚基大得多，并且包含其他多个蛋白质片段及核糖体RNA扩展片段。

参见

• 真核小核糖体亚基 (40S)

参考资料

1. 医学主题词表（MeSH）：60S+Ribosome+Subunits
2. Klinge, S; Voigts-Hoffmann, F; Leibundgut, M; Arpagaus, S; Ban, N. Crystal structure of the eukaryotic 60S ribosomal subunit in complex with initiation factor 6. Science. 2011, 334 (6058): 941–948. PMID 22052974. doi:10.1126/science.1211204.
3. Ben-Shem, A; Garreau; de Loubresse, N; Melnikov, S; Jenner, L; Yusupova, G; Yusupov, M. The structure of the eukaryotic ribosome at 3.0 Å resolution. Science. Dec 2011, 334 (6062): 1524–1529. PMID 22096102. doi:10.1126/science.1212642.
4. Ban, N; Nissen, P; Hansen, J; Moore, PB; Steitz, TA. The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science. Aug 2000, 289 (5481): 905–920. PMID 10937989. doi:10.1126/science.289.5481.905.
5. Cate, JH; Yusupov, MM; Yusupova, GZ; Earnest, TN; Noller, HF. X-ray crystal structures of 70S ribosome functional complexes. Science. Sep 1999, 285 (5436): 2095–2104. PMID 10497122. doi:10.1126/science.285.5436.2095.
6. Yusupov, MM; Yusupova, GZ; Baucom, A; Lieberman, K; Earnest, TN; Cate, JH; Noller, HF. Crystal structure of the ribosome at 5.5 A resolution. Science. May 2001, 292 (5518): 883–896. PMID 11283358. doi:10.1126/science.1060089.

外部链接

• Ribosomal Protein Gene Database (RPG) （页面存档备份，存于互联网档案馆）